Genetic manipulation of the mouse genome is essential for understanding gene function and for discovering the genetic and molecular basis of human disease. Thus, efficient use of genetically modified mouse models can enhance the potential for the development of targeted therapeutics and effective prevention strategies.
Antibodies provide powerful tools for research and diagnostic purposes. Antibodies are both highly sensitive and highly specific for particular epitopes, which makes them ideal reagents for detecting and quantifying a broad array of targets, from drugs to serum proteins to microorganisms.
Innovative research devices can be a great help in discovering phenomena that cannot be discovered with existing equipment. Such devices can contribute a great deal to the power and practical value of new technologies.
To accelerate scientific discoveries and to benefit the greater research community, principal investigators and funding recipient institutions are expected to ensure broad and timely dissemination of their research resources.
Tool Compounds are small molecular weight compounds of known structure from the literature acting as agonists, activators, antagonists and inhibitors. Tool compounds are often use in drug discovery for target validation.